The options.
WEBMAIL
Through a browser, at your domain followed by /webmail.
Nothing to set up. Works anywhere.
A MAIL CLIENT ON A COMPUTER
An application that connects to the server.
Works offline, and more comfortable for heavy use.
A MAIL APP ON A PHONE
The same, on a mobile device.
WHAT MOST PEOPLE USE
A phone app plus webmail, or a phone app plus a desktop client.
WHAT DETERMINES THE SETUP
Whether you use several devices Whether you need offline access How much mail you keep
THE CRITICAL DECISION
IMAP or POP.
That determines whether your mail stays on the server and syncs across devices.
Choose deliberately. Changing later is disruptive.
WHERE TO GET SETTINGS
cPanel, Email Accounts, connect devices.
It lists everything needed for any client.
WHAT TO USE
IMAP, for almost everyone.